Notable People
- Frances Dorothy Acomb, historian and academic
- Mary Amdur, scientist, investigated the 1948 Donora smog
- Robert Costanza, ecological economist
- Devra Davis, scientist, investigated the 1948 Donora smog
- Arnold “Pope” Galiffa, All-American and professional gridiron football player; inductee to the College Football Hall of Fame
- Ken Griffey Jr. “The Kid”, baseball player and Baseball Hall of Fame inductee
- Ken Griffey Sr., baseball player; his father was Joseph “Buddy” Griffey, a local athlete who was a teammate of Stan Musial on the Donora High School baseball team.
- Stan “The Man” Musial, baseball player with the St. Louis Cardinals and an inductee to the Baseball Hall of Fame
- Reggie Walton, United States District Judge for the District of Columbia, appointed in 2001 by President George W. Bush